Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

BACKGROUND: Plasmodium 18S rRNA is a biomarker used to monitor blood-stage infections in malaria clinical trials. Plasmodium sporozoites also express this biomarker, and there is conflicting evidence about how long sporozoite-derived 18S rRNA persists in peripheral blood. If present in blood for an...

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Detalles Bibliográficos
Autores principales: Murphy, Sean C., Ishizuka, Andrew S., Billman, Zachary P., Olsen, Tayla M., Seilie, Annette M., Chang, Ming, Smith, Nahum, Chuenchob, Vorada, Chakravarty, Sumana, Sim, B. Kim Lee, Kappe, Stefan H. I., Hoffman, Stephen L., Seder, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062992/
https://www.ncbi.nlm.nih.gov/pubmed/30053881
http://dx.doi.org/10.1186/s12936-018-2422-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062992/
https://www.ncbi.nlm.nih.gov/pubmed/30053881
http://dx.doi.org/10.1186/s12936-018-2422-2

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