Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2/3 Demethylases GSKJ4 Inhibitor via Protein Kinase A

Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both rapid disease progression and drug resistance occurrence. Therefore, new therapeutic approaches are demanded. Epigenetic marks play a relevant role in AM...

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Detalles Bibliográficos
Autores principales: Illiano, Michela, Conte, Mariarosaria, Sapio, Luigi, Nebbioso, Angela, Spina, Annamaria, Altucci, Lucia, Naviglio, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063003/
https://www.ncbi.nlm.nih.gov/pubmed/30079022
http://dx.doi.org/10.3389/fphar.2018.00792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063003/
https://www.ncbi.nlm.nih.gov/pubmed/30079022
http://dx.doi.org/10.3389/fphar.2018.00792

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