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Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA

BACKGROUND: Currently, resistance to tyrosine kinase inhibitors, such as gefitinib, has become a major obstacle in improving the clinical outcome of patients with metastatic and advanced-stage esophageal squamous cell carcinoma (ESCC). While cell behavior can be modulated by long non-coding RNAs (ln...

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Detalles Bibliográficos
Autores principales:	Kang, Min, Ren, Meiping, Li, Yan, Fu, Yuqiong, Deng, Minmin, Li, Changping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063009/ https://www.ncbi.nlm.nih.gov/pubmed/30049286 http://dx.doi.org/10.1186/s13046-018-0845-9

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