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A Small β-Carboline Derivative “B-9-3” Modulates TGF-β Signaling Pathway Causing Tumor Regression in Vivo

Targeting tumor microenvironment (TME) is crucial in order to overcome the anti-cancer therapy resistance. In this study, we report the antitumor activity of a newly synthesized β-carboline derivative “B-9-3.” Here, this small molecule showed a promising antitumor activity in vivo along with an enha...

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Detalles Bibliográficos
Autores principales:	Zhong, Hui, Daoud, Abdelkader, Han, Jichun, An, Xiaohong, Qiao, Caili, Duan, Lanlan, Wang, Yichuan, Chen, Zhenfeng, Zhou, Jia, Shang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063040/ https://www.ncbi.nlm.nih.gov/pubmed/30079021 http://dx.doi.org/10.3389/fphar.2018.00788

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