Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages

Some of the fastest evolving regions of the human genome are conserved noncoding elements with many human-specific DNA substitutions. These human accelerated regions (HARs) are enriched nearby regulatory genes, and several HARs function as developmental enhancers. To investigate if this evolutionary...

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Detalles Bibliográficos
Autores principales: Kostka, Dennis, Holloway, Alisha K, Pollard, Katherine S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063267/
https://www.ncbi.nlm.nih.gov/pubmed/29897475
http://dx.doi.org/10.1093/molbev/msy109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063267/
https://www.ncbi.nlm.nih.gov/pubmed/29897475
http://dx.doi.org/10.1093/molbev/msy109

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