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Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages
Some of the fastest evolving regions of the human genome are conserved noncoding elements with many human-specific DNA substitutions. These human accelerated regions (HARs) are enriched nearby regulatory genes, and several HARs function as developmental enhancers. To investigate if this evolutionary...
Autores principales: | Kostka, Dennis, Holloway, Alisha K, Pollard, Katherine S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063267/ https://www.ncbi.nlm.nih.gov/pubmed/29897475 http://dx.doi.org/10.1093/molbev/msy109 |
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