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The Human Cell Atlas: Technical approaches and challenges

The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort have the potential to transform many aspects of fundamental biology and clinical practice. Here, we di...

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Detalles Bibliográficos
Autores principales: Hon, Chung-Chau, Shin, Jay W, Carninci, Piero, Stubbington, Michael J T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063304/
https://www.ncbi.nlm.nih.gov/pubmed/29092000
http://dx.doi.org/10.1093/bfgp/elx029
Descripción
Sumario:The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort have the potential to transform many aspects of fundamental biology and clinical practice. Here, we discuss the technical approaches that could be used today to generate such a resource and also the technical challenges that will be encountered.