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Mechanisms of protein toxicity in neurodegenerative diseases

Protein toxicity can be defined as all the pathological changes that ensue from accumulation, mis-localization, and/or multimerization of disease-specific proteins. Most neurodegenerative diseases manifest protein toxicity as one of their key pathogenic mechanisms, the details of which remain unclea...

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Detalles Bibliográficos
Autores principales: Chung, Chang Geon, Lee, Hyosang, Lee, Sung Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063327/
https://www.ncbi.nlm.nih.gov/pubmed/29947927
http://dx.doi.org/10.1007/s00018-018-2854-4