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Mechanisms of protein toxicity in neurodegenerative diseases
Protein toxicity can be defined as all the pathological changes that ensue from accumulation, mis-localization, and/or multimerization of disease-specific proteins. Most neurodegenerative diseases manifest protein toxicity as one of their key pathogenic mechanisms, the details of which remain unclea...
Autores principales: | Chung, Chang Geon, Lee, Hyosang, Lee, Sung Bae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063327/ https://www.ncbi.nlm.nih.gov/pubmed/29947927 http://dx.doi.org/10.1007/s00018-018-2854-4 |
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