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Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression

Neurogenesis continues in the post-developmental brain throughout life. The ability to stimulate the production of new neurones requires both quiescent and actively proliferating pools of neural stem cells (NSCs). Actively proliferating NSCs ensure that neurogenic demand can be met, whilst the quies...

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Detalles Bibliográficos
Autores principales: Collins, Steven J., Tumpach, Carolin, Groveman, Bradley R., Drew, Simon C., Haigh, Cathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063333/
https://www.ncbi.nlm.nih.gov/pubmed/29574582
http://dx.doi.org/10.1007/s00018-018-2790-3