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Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression?
INTRODUCTION: Past trials of buprenorphine (BUP) in the treatment of major depressive disorder (MDD) have displayed favorable results, although its clinical utility was limited by the risk of abuse or physical dependence. By combining BUP with samidorphan (SAM), the euphoric high is negated by an op...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
College of Psychiatric & Neurologic Pharmacists
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063454/ https://www.ncbi.nlm.nih.gov/pubmed/30155392 http://dx.doi.org/10.9740/mhc.2018.07.175 |