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Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression?

INTRODUCTION: Past trials of buprenorphine (BUP) in the treatment of major depressive disorder (MDD) have displayed favorable results, although its clinical utility was limited by the risk of abuse or physical dependence. By combining BUP with samidorphan (SAM), the euphoric high is negated by an op...

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Detalles Bibliográficos
Autores principales:	Peckham, Alyssa M., De La Cruz, Austin, Dufresne, Robert L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	College of Psychiatric & Neurologic Pharmacists 2018
Materias:	Review of Drugs/Pharmacotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063454/ https://www.ncbi.nlm.nih.gov/pubmed/30155392 http://dx.doi.org/10.9740/mhc.2018.07.175

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