Cargando…
Insights into the ubiquitin transfer cascade catalyzed by the Legionella effector SidC
The causative agent of Legionnaires’ disease, Legionella pneumophila, delivers more than 330 virulent effectors to its host to establish an intracellular membrane-bound organelle called the Legionella containing vacuole. Among the army of Legionella effectors, SidC and its paralog SdcA have been ide...
Autores principales: | Wasilko, David Jon, Huang, Qingqiu, Mao, Yuxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063727/ https://www.ncbi.nlm.nih.gov/pubmed/30015617 http://dx.doi.org/10.7554/eLife.36154 |
Ejemplares similares
-
Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome
por: Luo, Xi, et al.
Publicado: (2015) -
Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ
por: Sulpizio, Alan, et al.
Publicado: (2019) -
The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector
por: Akturk, Anil, et al.
Publicado: (2018) -
A Bifunctional Enzyme of Legionella that Distinctly Regulates Phosphoribosyl Ubiquitination of the SidE Family Effectors
por: Jiao, Jun, et al.
Publicado: (2022) -
Structural basis for the toxicity of Legionella pneumophila effector SidH
por: Sharma, Rahul, et al.
Publicado: (2023)