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Cryo-EM structure of the mitochondrial calcium uniporter

The mitochondrial calcium uniporter is a highly selective calcium channel localized to the inner mitochondrial membrane. Here, we describe the structure of an MCU ortholog from the fungus Neosartorya fischeri (NfMCU) determined to 3.8 Å resolution by phase-plate cryo-electron microscopy. The channel...

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Detalles Bibliográficos
Autores principales:	Nguyen, Nam X., Armache, Jean-Paul, Lee, Changkeun, Yang, Yi, Zeng, Weizhong, Mootha, Vamsi K., Cheng, Yifan, Bai, Xiao-chen, Jiang, Youxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063787/ https://www.ncbi.nlm.nih.gov/pubmed/29995855 http://dx.doi.org/10.1038/s41586-018-0333-6

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