Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis

BACKGROUND: Despite increasing ethical standards for conducting animal research, death is still often used as an endpoint in mouse sepsis studies. Recently, the Murine Sepsis Score (MSS), Mouse Clinical Assessment Score for Sepsis (M-CASS), and Mouse Grimace Scale (MGS) were developed as surrogate e...

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Detalles Bibliográficos
Autores principales: Mai, Safiah H. C., Sharma, Neha, Kwong, Andrew C., Dwivedi, Dhruva J., Khan, Momina, Grin, Peter M., Fox-Robichaud, Alison E., Liaw, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063809/
https://www.ncbi.nlm.nih.gov/pubmed/30054760
http://dx.doi.org/10.1186/s40635-018-0184-3

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