Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin

Although previous studies have indicated important roles of palmitate, a saturated fatty acid, in the pathogenesis of nonalcoholic fatty liver disease (NAFLD), it remains unclear how palmitate contributes to inflammation and fibrosis in the liver. Administration of palmitate in high fat diet (HFD)-f...

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Detalles Bibliográficos
Autores principales: Ogawa, Yuji, Imajo, Kento, Honda, Yasushi, Kessoku, Takaomi, Tomeno, Wataru, Kato, Shingo, Fujita, Koji, Yoneda, Masato, Saito, Satoru, Saigusa, Yusuke, Hyogo, Hideyuki, Sumida, Yoshio, Itoh, Yoshito, Eguchi, Kosei, Yamanaka, Takeharu, Wada, Koichiro, Nakajima, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063851/
https://www.ncbi.nlm.nih.gov/pubmed/30054551
http://dx.doi.org/10.1038/s41598-018-29735-6

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