Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis

Contact inhibition enables noncancerous cells to cease proliferation and growth when they contact each other. This characteristic is lost when cells undergo malignant transformation, leading to uncontrolled proliferation and solid tumor formation. Here we report that autophagy is compromised in cont...

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Detalles Bibliográficos
Autores principales: Pavel, Mariana, Renna, Maurizio, Park, So Jung, Menzies, Fiona M., Ricketts, Thomas, Füllgrabe, Jens, Ashkenazi, Avraham, Frake, Rebecca A., Lombarte, Alejandro Carnicer, Bento, Carla F., Franze, Kristian, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063886/
https://www.ncbi.nlm.nih.gov/pubmed/30054475
http://dx.doi.org/10.1038/s41467-018-05388-x

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