Long-term Rescue of Photoreceptors in a Rodent Model of Retinitis Pigmentosa Associated with MERTK Mutation

MERTK mutation reduces the ability of retinal pigment epithelial (RPE) cells to phagocytize the photoreceptor outer segments, which leads to accumulation of debris separating photoreceptors from RPE cells, resulting in their degeneration and loss of vision. In a rat model of Retinitis Pigmentosa due...

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Detalles Bibliográficos
Autores principales: Lorach, H., Kang, S., Dalal, R., Bhuckory, M. B., Quan, Y., Palanker, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063887/
https://www.ncbi.nlm.nih.gov/pubmed/30054542
http://dx.doi.org/10.1038/s41598-018-29631-z

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