Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain

Diabetes mellitus is a group of disorders characterized by prolonged high levels of circulating blood glucose. Type 1 diabetes is caused by decreased insulin production in the pancreas whereas type 2 diabetes may develop due to obesity and lack of exercise; it begins with insulin resistance whereby...

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Autores principales: Nikolakopoulou, Polyxeni, Chatzigeorgiou, Antonios, Kourtzelis, Ioannis, Toutouna, Louiza, Masjkur, Jimmy, Arps-Forker, Carina, Poser, Steven W., Rozman, Jan, Rathkolb, Birgit, Aguilar-Pimentel, Juan Antonio, Wolf, Eckhard, Klingenspor, Martin, Ollert, Markus, Schmidt-Weber, Carsten, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Tsata, Vasiliki, Monasor, Laura Sebastian, Troullinaki, Maria, Witt, Anke, Anastasiou, Vivian, Chrousos, George, Yi, Chun-Xia, García-Cáceres, Cristina, Tschöp, Matthias H., Bornstein, Stefan R., Androutsellis-Theotokis, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063949/
https://www.ncbi.nlm.nih.gov/pubmed/30054579
http://dx.doi.org/10.1038/s41598-018-29434-2

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