Hormetic dose response to (L)-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression

(L)-Ascorbic acid (vitamin C, AA) exhibits anti-cancer effects with high-dose treatment through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. The anti-cancer effects of (L)-ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a tr...

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Detalles Bibliográficos
Autores principales: Cho, Sungrae, Chae, Jin Sung, Shin, Hocheol, Shin, Yujeong, Song, Haeun, Kim, Youngwook, Yoo, Byong Chul, Roh, Kangsan, Cho, Seungchan, Kil, Eui-joon, Byun, Hee-seong, Cho, Sang-ho, Park, Seyeon, Lee, Sukchan, Yeom, Chang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063950/
https://www.ncbi.nlm.nih.gov/pubmed/30054560
http://dx.doi.org/10.1038/s41598-018-29386-7

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