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Effect of Thrombin-Induced MCP-1 and MMP-3 Production Via PAR1 Expression in Murine Intervertebral Discs
Structural changes in nucleus pulposus cells induce intervertebral disc (IVD) degeneration as a consequence of cytokine generation, biochemical products, and changes in the local environment. We have previously shown that inflammatory cytokines induce murine IVD (mIVD) angiogenesis and macrophage mi...
Autores principales: | Takayama, Yoshihiro, Ando, Takashi, Ichikawa, Jiro, Haro, Hirotaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063965/ https://www.ncbi.nlm.nih.gov/pubmed/30054581 http://dx.doi.org/10.1038/s41598-018-29669-z |
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