Seizure frequency can be reduced by changing intracranial pressure: A case report in drug-resistant epilepsy()

A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial. We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired...

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Detalles Bibliográficos
Autores principales: Uchida, Daiki, Fujimoto, Ayataka, Yamazoe, Tomohiro, Yamamoto, Takamichi, Enoki, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063982/
https://www.ncbi.nlm.nih.gov/pubmed/30062085
http://dx.doi.org/10.1016/j.ebcr.2017.12.005
Descripción
Sumario:A relationship between seizures and intracranial pressure (ICP) has been proposed, but not clearly identified. Whether changes in ICP can evoke seizures remains controversial. We report the case of a 23-year-old man who had undergone shunt surgery in childhood and later presented with focal impaired awareness seizures and behavior arrest. Seizures were uncontrolled despite 3 years of pharmacotherapy, but suddenly stopped after shunt removal. Our case supports the hypothesis that drug-resistant epilepsy can be influenced by changes in ICP. In particular, this case indicates that elevations in ICP may help reduce some seizures.

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