CNS distribution, signalling properties and central effects of G-protein coupled receptor 4

Information on the distribution and biology of the G-protein coupled receptor 4 (GPR4) in the brain is limited. It is currently thought that GPR4 couples to G(s) proteins and may mediate central respiratory sensitivity to CO(2). Using a knock-in mouse model, abundant GPR4 expression was detected in...

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Detalles Bibliográficos
Autores principales: Hosford, P.S., Mosienko, V., Kishi, K., Jurisic, G., Seuwen, K., Kinzel, B., Ludwig, M.G., Wells, J.A., Christie, I.N., Koolen, L., Abdala, A.P., Liu, B.H., Gourine, A.V., Teschemacher, A.G., Kasparov, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063991/
https://www.ncbi.nlm.nih.gov/pubmed/29894771
http://dx.doi.org/10.1016/j.neuropharm.2018.06.007

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