The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments

OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Pla...

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Detalles Bibliográficos
Autores principales: Wiegreffe, Daniel, Müller, Lydia, Steuck, Jens, Zeckzer, Dirk, Stadler, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064048/
https://www.ncbi.nlm.nih.gov/pubmed/30055643
http://dx.doi.org/10.1186/s13104-018-3633-x
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author Wiegreffe, Daniel
Müller, Lydia
Steuck, Jens
Zeckzer, Dirk
Stadler, Peter F.
author_facet Wiegreffe, Daniel
Müller, Lydia
Steuck, Jens
Zeckzer, Dirk
Stadler, Peter F.
author_sort Wiegreffe, Daniel
collection PubMed
description OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates.
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spelling pubmed-60640482018-07-31 The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments Wiegreffe, Daniel Müller, Lydia Steuck, Jens Zeckzer, Dirk Stadler, Peter F. BMC Res Notes Research Note OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates. BioMed Central 2018-07-28 /pmc/articles/PMC6064048/ /pubmed/30055643 http://dx.doi.org/10.1186/s13104-018-3633-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Wiegreffe, Daniel
Müller, Lydia
Steuck, Jens
Zeckzer, Dirk
Stadler, Peter F.
The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title_full The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title_fullStr The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title_full_unstemmed The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title_short The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
title_sort sierra platinum service for generating peak-calls for replicated chip-seq experiments
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064048/
https://www.ncbi.nlm.nih.gov/pubmed/30055643
http://dx.doi.org/10.1186/s13104-018-3633-x
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