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CD36 – a plausible modifier of disease phenotype in familial adenomatous polyposis

BACKGROUND: Familial adenomatous polyposis (FAP) is a well characterised genetic predisposition to early onset colorectal cancer (CRC) that is characterised by polyposis of the colon and rectum. Animal models have consistently suggested the role of modifier genes in determining disease phenotype, ye...

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Detalles Bibliográficos
Autores principales: Holmes, Merran, Connor, Toni, Oldmeadow, Christopher, Pockney, Peter G., Scott, Rodney J., Talseth-Palmer, Bente A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064055/
https://www.ncbi.nlm.nih.gov/pubmed/30065793
http://dx.doi.org/10.1186/s13053-018-0096-y