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Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress
Upregulation of histone acetylation plays a critical role in the dysregulation of transcription. It alters the structure of chromatin, which leads to the onset of cancer. Histone deacetylase inhibitors may therefore be a promising way to limit cancer progression. In this study, we examined the effec...
Autores principales: | Huang, Ying, Yang, Wuping, Zeng, Huihong, Hu, Chuan, Zhang, Yaqiong, Ding, Nanhua, Fan, Guangqin, Shao, Lijian, Kuang, Bohai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064062/ https://www.ncbi.nlm.nih.gov/pubmed/30065760 http://dx.doi.org/10.1186/s11658-018-0101-5 |
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