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Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts

OBJECTIVE: Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas characterized by high recurrence rates and early metastases. These tumors arise more frequently within neurofibromatosis type 1 (NF1) and present with resistance during standard chemotherapy leading to increased mort...

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Detalles Bibliográficos
Autores principales:	Fischer-Huchzermeyer, Susan, Chikobava, Levan, Stahn, Verena, Zangarini, Monique, Berry, Philip, Veal, Gareth J., Senner, Volker, Mautner, Victor F., Harder, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064132/ https://www.ncbi.nlm.nih.gov/pubmed/30055648 http://dx.doi.org/10.1186/s13104-018-3630-0

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