Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

BACKGROUND: Focal adhesion plays an essential role in tumour invasiveness and metastasis. Hippo component YAP has been widely reported to be involved in many aspects of tumour biology. However, its role in focal adhesion regulation in breast cancer remains unexplored. METHODS: Tissue microarray was...

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Detalles Bibliográficos
Autores principales: Shen, Jie, Cao, Beibei, Wang, Yatao, Ma, Chenshen, Zeng, Zhuo, Liu, Liang, Li, Xiaolan, Tao, Deding, Gong, Jianping, Xie, Daxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064138/
https://www.ncbi.nlm.nih.gov/pubmed/30055645
http://dx.doi.org/10.1186/s13046-018-0850-z

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