The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector

BACKGROUND: Agonists of TLR3 and TLR4 are effective immunoadjuvants for different types of vaccines. The mechanisms of their immunostimulatory action differ significantly; these differences are particularly critical for immunization with non-replicating adenovirus vectors (rAds) based vaccines. Unli...

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Detalles Bibliográficos
Autores principales: Lebedeva, Ekaterina, Bagaev, Alexander, Pichugin, Alexey, Chulkina, Marina, Lysenko, Andrei, Tutykhina, Irina, Shmarov, Maxim, Logunov, Denis, Naroditsky, Boris, Ataullakhanov, Ravshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064145/
https://www.ncbi.nlm.nih.gov/pubmed/30055563
http://dx.doi.org/10.1186/s12865-018-0264-x

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