Nefopam downregulates autophagy and c-Jun N-terminal kinase activity in the regulation of neuropathic pain development following spinal nerve ligation

BACKGROUND: Neurodegeneration is associated with changes in basal cellular function due to the dysregulation of autophagy. A recent study introduced the involvement of autophagy during spinal nerve ligation (SNL). Nefopam has shown potential for reducing neuropathic pain, but the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Oh, Seon-Hee, Yoon, Myung Ha, Lim, Kyung Joon, Yu, Byung Sik, Jee, In Gook, Jung, Ki Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064146/
https://www.ncbi.nlm.nih.gov/pubmed/30053799
http://dx.doi.org/10.1186/s12871-018-0559-8

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