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Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease
IgG4-related disease (IgG4RD) is a multi-organ disorder characterized by an elevated serum IgG4 level and IgG4-positive plasma cell infiltration of the affected organs, accompanied by tissue fibrosis and sclerosis. Although it can affect any organ, to our knowledge, no cases involving concurrent aut...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064692/ https://www.ncbi.nlm.nih.gov/pubmed/29491289 http://dx.doi.org/10.2169/internalmedicine.0190-17 |
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author | Shimazu, Yayoi Uchiyama, Tatsuki Mizumoto, Chisaki Takeoka, Tomoharu Tsuji, Masaaki Tomo, Kenjiro Takaori, Koji Sakai, Naoki Okuno, Tomoko Ohno, Tatsuharu |
author_facet | Shimazu, Yayoi Uchiyama, Tatsuki Mizumoto, Chisaki Takeoka, Tomoharu Tsuji, Masaaki Tomo, Kenjiro Takaori, Koji Sakai, Naoki Okuno, Tomoko Ohno, Tatsuharu |
author_sort | Shimazu, Yayoi |
collection | PubMed |
description | IgG4-related disease (IgG4RD) is a multi-organ disorder characterized by an elevated serum IgG4 level and IgG4-positive plasma cell infiltration of the affected organs, accompanied by tissue fibrosis and sclerosis. Although it can affect any organ, to our knowledge, no cases involving concurrent autoimmune neutropenia and thrombocytopenia have been reported. A 62-year-old man visited our hospital and was diagnosed with IgG4RD accompanied by interstitial pneumonitis, lymphadenopathy, and interstitial nephritis. During his clinical course, he developed autoimmune neutropenia and idiopathic thrombocytopenic purpura. Our case, invoving multiple hematological abnormalities, might help deepen our understanding of the pathophysiology of IgG4RD. |
format | Online Article Text |
id | pubmed-6064692 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-60646922018-07-30 Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease Shimazu, Yayoi Uchiyama, Tatsuki Mizumoto, Chisaki Takeoka, Tomoharu Tsuji, Masaaki Tomo, Kenjiro Takaori, Koji Sakai, Naoki Okuno, Tomoko Ohno, Tatsuharu Intern Med Case Report IgG4-related disease (IgG4RD) is a multi-organ disorder characterized by an elevated serum IgG4 level and IgG4-positive plasma cell infiltration of the affected organs, accompanied by tissue fibrosis and sclerosis. Although it can affect any organ, to our knowledge, no cases involving concurrent autoimmune neutropenia and thrombocytopenia have been reported. A 62-year-old man visited our hospital and was diagnosed with IgG4RD accompanied by interstitial pneumonitis, lymphadenopathy, and interstitial nephritis. During his clinical course, he developed autoimmune neutropenia and idiopathic thrombocytopenic purpura. Our case, invoving multiple hematological abnormalities, might help deepen our understanding of the pathophysiology of IgG4RD. The Japanese Society of Internal Medicine 2018-02-28 2018-07-01 /pmc/articles/PMC6064692/ /pubmed/29491289 http://dx.doi.org/10.2169/internalmedicine.0190-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Shimazu, Yayoi Uchiyama, Tatsuki Mizumoto, Chisaki Takeoka, Tomoharu Tsuji, Masaaki Tomo, Kenjiro Takaori, Koji Sakai, Naoki Okuno, Tomoko Ohno, Tatsuharu Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title | Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title_full | Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title_fullStr | Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title_full_unstemmed | Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title_short | Concurrent Autoimmune Neutropenia and Idiopathic Thrombocytopenic Purpura Associated with IgG4-related Diease |
title_sort | concurrent autoimmune neutropenia and idiopathic thrombocytopenic purpura associated with igg4-related diease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064692/ https://www.ncbi.nlm.nih.gov/pubmed/29491289 http://dx.doi.org/10.2169/internalmedicine.0190-17 |
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