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Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm

We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine an...

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Autores principales: Nakamichi, Akiko, Ocho, Kazuki, Oka, Kosuke, Yasuda, Miho, Hasegawa, Kou, Iwamuro, Masaya, Obika, Mikako, Rai, Kammei, Otsuka, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064704/
https://www.ncbi.nlm.nih.gov/pubmed/29491282
http://dx.doi.org/10.2169/internalmedicine.0063-17
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author Nakamichi, Akiko
Ocho, Kazuki
Oka, Kosuke
Yasuda, Miho
Hasegawa, Kou
Iwamuro, Masaya
Obika, Mikako
Rai, Kammei
Otsuka, Fumio
author_facet Nakamichi, Akiko
Ocho, Kazuki
Oka, Kosuke
Yasuda, Miho
Hasegawa, Kou
Iwamuro, Masaya
Obika, Mikako
Rai, Kammei
Otsuka, Fumio
author_sort Nakamichi, Akiko
collection PubMed
description We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. The occurrence of central diabetes insipidus with hyperthyroidism was revealed on the basis of pituitary magnetic resonance imaging, a water deprivation test and a desmopressin test. The clinical co-existence of diabetes insipidus and hyperthyroidism is very rare; however, the complication should be considered when hypernatremia and/or dehydration progress in patients with Graves's disease as a common autoimmune-related etiology.
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spelling pubmed-60647042018-07-30 Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm Nakamichi, Akiko Ocho, Kazuki Oka, Kosuke Yasuda, Miho Hasegawa, Kou Iwamuro, Masaya Obika, Mikako Rai, Kammei Otsuka, Fumio Intern Med Case Report We herein report a case of central diabetes insipidus complicated with thyroid storm. A middle-aged woman who was receiving treatment for Graves' disease suddenly complained of polydipsia, polyuria and general fatigue. Laboratory tests showed hyperthyroidism, hypernatremia, hypoosmolar urine and a decreased plasma vasopressin level. The occurrence of central diabetes insipidus with hyperthyroidism was revealed on the basis of pituitary magnetic resonance imaging, a water deprivation test and a desmopressin test. The clinical co-existence of diabetes insipidus and hyperthyroidism is very rare; however, the complication should be considered when hypernatremia and/or dehydration progress in patients with Graves's disease as a common autoimmune-related etiology. The Japanese Society of Internal Medicine 2018-02-28 2018-07-01 /pmc/articles/PMC6064704/ /pubmed/29491282 http://dx.doi.org/10.2169/internalmedicine.0063-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nakamichi, Akiko
Ocho, Kazuki
Oka, Kosuke
Yasuda, Miho
Hasegawa, Kou
Iwamuro, Masaya
Obika, Mikako
Rai, Kammei
Otsuka, Fumio
Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title_full Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title_fullStr Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title_full_unstemmed Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title_short Manifestation of Central Diabetes Insipidus in a Patient with Thyroid Storm
title_sort manifestation of central diabetes insipidus in a patient with thyroid storm
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064704/
https://www.ncbi.nlm.nih.gov/pubmed/29491282
http://dx.doi.org/10.2169/internalmedicine.0063-17
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