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Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation
Pseudomonas aeruginosa (P.a) is a pathogen causing significant morbidity and mortality, in particular, in hospital patients undergoing ventilation and in patients with cystic fibrosis. Among the virulence factors secreted or injected into host cells, the physiopathological relevance of type II secre...
Autores principales: | Bastaert, Fabien, Kheir, Saadé, Saint-Criq, Vinciane, Villeret, Bérengère, Dang, Pham My-Chan, El-Benna, Jamel, Sirard, Jean-Claude, Voulhoux, Romé, Sallenave, Jean-Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064941/ https://www.ncbi.nlm.nih.gov/pubmed/30083156 http://dx.doi.org/10.3389/fimmu.2018.01675 |
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