Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma

Background: Overexpression of EGFR is a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). Patients with HNSCC who respond to EGFR-targeted tyrosine kinase inhibitors (TKIs) eventually develop acquired resistance. Strategies to identify HNSCC patients likely to benefit from...

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Detalles Bibliográficos
Autores principales: Baker, Lauren C. J., Sikka, Arti, Price, Jonathan M., Boult, Jessica K. R., Lepicard, Elise Y., Box, Gary, Jamin, Yann, Spinks, Terry J., Kramer-Marek, Gabriela, Leach, Martin O., Eccles, Suzanne A., Box, Carol, Robinson, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064942/
https://www.ncbi.nlm.nih.gov/pubmed/30083516
http://dx.doi.org/10.3389/fonc.2018.00271

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