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GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae

The chromosomes of many eukaryotes have regions of high GC content interspersed with regions of low GC content. In the yeast Saccharomyces cerevisiae, high-GC regions are often associated with high levels of meiotic recombination. In this study, we constructed URA3 genes that differ substantially in...

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Detalles Bibliográficos
Autores principales: Kiktev, Denis A., Sheng, Ziwei, Lobachev, Kirill S., Petes, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064992/
https://www.ncbi.nlm.nih.gov/pubmed/29987035
http://dx.doi.org/10.1073/pnas.1807334115