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C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune neuroinflammatory disease. In contrast to multiple sclerosis, autoantibodies against aquaporin-4 (AQP4) expressed on astrocytic end-feet have been exclusively detected in sera of NMOSD patients. Several lines of evidence suggested that...

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Detalles Bibliográficos
Autores principales:	Piatek, Paweł, Domowicz, Małgorzata, Lewkowicz, Natalia, Przygodzka, Patrycja, Matysiak, Mariola, Dzitko, Katarzyna, Lewkowicz, Przemysław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065055/ https://www.ncbi.nlm.nih.gov/pubmed/30083159 http://dx.doi.org/10.3389/fimmu.2018.01694

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