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Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity
BACKGROUND/AIMS: Free radical scavenger tempol is a protective antioxidant against ischemic injury. Tubular epithelial apoptosis is one of the main changes in the renal ischemia/reperfusion (I/R) injury. Meanwhile some proteins related with apoptosis and inflammation are also involved in renal I/R i...
Autores principales: | Zhang, Gensheng, Wang, Qin, Wang, Wenwen, Yu, Minghua, Zhang, Suping, Xu, Nan, Zhou, Suhan, Cao, Xiaoyun, Fu, Xiaodong, Ma, Zufu, Liu, Ruisheng, Mao, Jianhua, Lai, En Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065105/ https://www.ncbi.nlm.nih.gov/pubmed/29870982 http://dx.doi.org/10.1159/000490338 |
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