Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica

Streptomycin and spectinomycin are antibiotics that bind to the bacterial ribosome and perturb protein synthesis. The clinically most prevalent bacterial resistance mechanism is their chemical modification by aminoglycoside-modifying enzymes such as aminoglycoside nucleotidyltransferases (ANTs). Aad...

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Detalles Bibliográficos
Autores principales: Stern, Ana Laura, Van der Verren, Sander Egbert, Kanchugal P, Sandesh, Näsvall, Joakim, Gutiérrez-de-Terán, Hugo, Selmer, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065190/
https://www.ncbi.nlm.nih.gov/pubmed/29871922
http://dx.doi.org/10.1074/jbc.RA118.003989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065190/
https://www.ncbi.nlm.nih.gov/pubmed/29871922
http://dx.doi.org/10.1074/jbc.RA118.003989

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