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Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages)

Diabetic patients exhibit serum AGE accumulation, which is associated with reactive oxygen species (ROS) production and diabetic cardiomyopathy. ROS-induced PKCδ activation is linked to mitochondrial dysfunction in human cells. However, the role of PKCδ in cardiac and mitochondrial dysfunction cause...

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Detalles Bibliográficos
Autores principales:	Yang, Yao-Chih, Tsai, Cheng-Yen, Chen, Chien-Lin, Kuo, Chia-Hua, Hou, Chien-Wen, Cheng, Shi-Yann, Aneja, Ritu, Huang, Chih-Yang, Kuo, Wei-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JKL International LLC 2018
Materias:	Orginal Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065295/ https://www.ncbi.nlm.nih.gov/pubmed/30090653 http://dx.doi.org/10.14336/AD.2017.0924

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