Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis

Hepatic lipogenesis is aberrantly induced in nonalcoholic fatty liver disease (NAFLD) via activation of the LXR-SREBP1c pathway. To date, a number of protein factors impinging on the transcriptional activity of LXR and SREBP1c have been elucidated. However, whether this regulatory axis interfaces wi...

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Detalles Bibliográficos
Autores principales: Zhao, Xu-Yun, Xiong, Xuelian, Liu, Tongyu, Mi, Lin, Peng, Xiaoling, Rui, Crystal, Guo, Liang, Li, Siming, Li, Xiaoying, Lin, Jiandie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065308/
https://www.ncbi.nlm.nih.gov/pubmed/30061575
http://dx.doi.org/10.1038/s41467-018-05383-2

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