Cargando…

Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes

Targeted genetic dissection of tissues to identify precise cell populations has vast biological and therapeutic applications. Here we develop an approach, through the packaging and delivery of 4-hydroxytamoxifen liposomes (LiTMX), that enables localized induction of CreER(T2) recombinase in mice. Ou...

Descripción completa

Detalles Bibliográficos
Autores principales: Ransom, Ryan C., Foster, Deshka S., Salhotra, Ankit, Jones, Ruth Ellen, Marshall, Clement D., Leavitt, Tripp, Murphy, Matthew P., Moore, Alessandra L., Blackshear, Charles P., Brett, Elizabeth A., Wan, Derrick C., Longaker, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065311/
https://www.ncbi.nlm.nih.gov/pubmed/30061668
http://dx.doi.org/10.1038/s41467-018-05436-6