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Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes
Targeted genetic dissection of tissues to identify precise cell populations has vast biological and therapeutic applications. Here we develop an approach, through the packaging and delivery of 4-hydroxytamoxifen liposomes (LiTMX), that enables localized induction of CreER(T2) recombinase in mice. Ou...
Autores principales: | Ransom, Ryan C., Foster, Deshka S., Salhotra, Ankit, Jones, Ruth Ellen, Marshall, Clement D., Leavitt, Tripp, Murphy, Matthew P., Moore, Alessandra L., Blackshear, Charles P., Brett, Elizabeth A., Wan, Derrick C., Longaker, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065311/ https://www.ncbi.nlm.nih.gov/pubmed/30061668 http://dx.doi.org/10.1038/s41467-018-05436-6 |
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