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Exosome-mediated transfer of lncRNA-SNHG14 promotes trastuzumab chemoresistance in breast cancer

Currently, resistance to trastuzumab, a human epidermal growth factor receptor 2 (HER2) inhibitor, has become an important obstacle to improving the clinical outcome of patients with advanced HER2(+) breast cancer. While cell behavior may be modulated by long non-coding RNAs (lncRNAs), the contribut...

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Detalles Bibliográficos
Autores principales: Dong, Huaying, Wang, Wei, Chen, Ru, Zhang, Yu, Zou, Kejian, Ye, Mulin, He, Xionghui, Zhang, Fan, Han, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065402/
https://www.ncbi.nlm.nih.gov/pubmed/30015837
http://dx.doi.org/10.3892/ijo.2018.4467