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LRP1 is required for novobiocin-mediated fibronectin turnover
Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the...
Autores principales: | Boel, Natasha Marie-Eraine, Hunter, Morgan Campbell, Edkins, Adrienne Lesley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065439/ https://www.ncbi.nlm.nih.gov/pubmed/30061663 http://dx.doi.org/10.1038/s41598-018-29531-2 |
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