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Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

Chemotherapy for suppressing tumor growth and metastasis tends to induce various effects on other organs. Using AZD7762, an inhibitor of checkpoint kinase (Chk) 1 and 2, the present study examined its effect on mammary tumor cells in addition to bone cells (osteoclasts, osteoblasts and osteocytes),...

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Detalles Bibliográficos
Autores principales:	Wang, Luqi, Wang, Yue, Chen, Andy, Jalali, Aydin, Liu, Shengzhi, Guo, Yunxia, Na, Sungsoo, Nakshatri, Harikrishna, Li, Bai-Yan, Yokota, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065446/ https://www.ncbi.nlm.nih.gov/pubmed/30015873 http://dx.doi.org/10.3892/ijo.2018.4481

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