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Update on Multiple Endocrine Neoplasia Type 2: Focus on Medullary Thyroid Carcinoma
Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant hereditary cancer syndrome caused by missense gain-of-function mutations in the RET proto-oncogene on chromosome 10. Specific RET mutations can predispose toward a particular phenotype and clinical course, with strong genotype–pheno...
Autores principales: | Raue, Friedhelm, Frank-Raue, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065486/ https://www.ncbi.nlm.nih.gov/pubmed/30087948 http://dx.doi.org/10.1210/js.2018-00178 |
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