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Reduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery
INTRODUCTION: A reduction-sensitive CD44-positive tumor-targetable drug delivery system for doxorubicin (DOX) delivery was developed based on hyaluronic acid (HA)-grafted polymers. MATERIALS AND METHODS: HA was conjugated with folic acid (FA) via a reduction-sensitive disulfide linkage to form an am...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065576/ https://www.ncbi.nlm.nih.gov/pubmed/30100720 http://dx.doi.org/10.2147/IJN.S165359 |