Cargando…

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive (ALK+) and NPM-ALK-negative (ALK−) anaplastic large-cell lymphoma (ALCL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hassler, Melanie R., Pulverer, Walter, Lakshminarasimhan, Ranjani, Redl, Elisa, Hacker, Julia, Garland, Gavin D., Merkel, Olaf, Schiefer, Ana-Iris, Simonitsch-Klupp, Ingrid, Kenner, Lukas, Weisenberger, Daniel J., Weinhaeusel, Andreas, Turner, Suzanne D., Egger, Gerda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066089/ https://www.ncbi.nlm.nih.gov/pubmed/27705804 http://dx.doi.org/10.1016/j.celrep.2016.09.018

Ejemplares similares

Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation
por: Merkel, Olaf, et al.
Publicado: (2015)

BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL
por: Garland, Gavin D., et al.
Publicado: (2021)

Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2′-deoxycytidine in anaplastic large cell lymphoma
por: Hassler, Melanie R., et al.
Publicado: (2012)

Identification of tumor tissue-derived DNA methylation biomarkers for the detection and therapy response evaluation of metastatic castration resistant prostate cancer in liquid biopsies
por: Dillinger, Thomas, et al.
Publicado: (2022)

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress
por: Malcolm, Tim I. M., et al.
Publicado: (2016)

An Exploration into the Origins and Pathogenesis of Anaplastic Large Cell Lymphoma, Anaplastic Lymphoma Kinase (ALK)-Positive
por: Turner, Suzanne D.
Publicado: (2017)

The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis
por: Ducray, Stephen P., et al.
Publicado: (2019)

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma
por: Prutsch, Nicole, et al.
Publicado: (2018)

Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma
por: Zrimšek, Maša, et al.
Publicado: (2022)

Is breast implant-associated anaplastic large cell lymphoma a hazard of breast implant surgery?
por: Fitzal, Florian, et al.
Publicado: (2019)

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma
por: Prutsch, Nicole, et al.
Publicado: (2020)

Epigenomics of cancer – emerging new concepts
por: Hassler, Melanie R., et al.
Publicado: (2012)

Stem cell hunt in NHL
por: Merkel, Olaf, et al.
Publicado: (2015)

Transformed mucosa‐associated lymphoid tissue lymphomas: A single institution retrospective study including polymerase chain reaction‐based clonality analysis
por: Kiesewetter, Barbara, et al.
Publicado: (2019)

Myelomonocytic Skewing In Vitro Discriminates Subgroups of Patients with Myelofibrosis with A Different Phenotype, A Different Mutational Profile and Different Prognosis
por: Geissler, Klaus, et al.
Publicado: (2020)

Cell of Origin and Immunologic Events in the Pathogenesis of Breast Implant–Associated Anaplastic Large-Cell Lymphoma
por: Turner, Suzanne D., et al.
Publicado: (2020)

Influence of TP53 Mutation on Survival of Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era
por: Porpaczy, Edit, et al.
Publicado: (2021)

Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma
por: Liang, Huan-Chang, et al.
Publicado: (2021)

PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma
por: Garces de los Fayos Alonso, I., et al.
Publicado: (2022)

PD‐L1 and PD1 expression in post‐transplantation lymphoproliferative disease (PTLD) of childhood and adolescence: An inter‐ and intra‐individual descriptive study covering the whole spectrum of PTLD categories
por: Schiefer, Ana‐Iris, et al.
Publicado: (2019)

Research progresses in the pathogenesis of anaplastic large cell lymphoma
por: Shi, Xiao-Lan, et al.
Publicado: (2011)

Anaplastic Large Cell Lymphoma: Molecular Pathogenesis and Treatment
por: Zhang, Xin-Rui, et al.
Publicado: (2022)

Anaplastic Thyroid Cancer: A Review of Epidemiology, Pathogenesis, and Treatment
por: Nagaiah, Govardhanan, et al.
Publicado: (2011)

Aberrant Expression of and Cell Death Induction by Engagement of the MHC-II Chaperone CD74 in Anaplastic Large Cell Lymphoma (ALCL)
por: Wurster, Kathrin D., et al.
Publicado: (2021)

Difficulties in the differential diagnosis of large solitary pulmonary cysts
por: Frick, Anna Elisabeth, et al.
Publicado: (2021)

Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer
por: Ilijazi, Dafina, et al.
Publicado: (2020)

Successful Clarithromycin Monotherapy in a Patient with Primary Follicular Lymphoma of the Duodenum
por: Kiesewetter, Barbara, et al.
Publicado: (2018)

Depth of Remission Following First-Line Treatment Is an Independent Prognostic Marker for Progression-Free Survival in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
por: Kiesewetter, Barbara, et al.
Publicado: (2020)

Multiplexed DNA Methylation Analysis in Colorectal Cancer Using Liquid Biopsy and Its Diagnostic and Predictive Value
por: Pulverer, Walter, et al.
Publicado: (2021)

Anaplastic thyroid cancer: Pathogenesis, prognostic factors and genetic landscape (Review)
por: Alhejaily, Abdul-Mohsen G., et al.
Publicado: (2023)

Analysis and Visualization Tool for Targeted Amplicon Bisulfite Sequencing on Ion Torrent Sequencers
por: Pabinger, Stephan, et al.
Publicado: (2016)

Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis
por: Redl, Elisa, et al.
Publicado: (2020)

Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level
por: Fatemi, Mehrnaz, et al.
Publicado: (2005)

DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer
por: Gampenrieder, Simon Peter, et al.
Publicado: (2018)

The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas
por: Garces de los Fayos Alonso, Ines, et al.
Publicado: (2018)

Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria
por: Gisslinger, H, et al.
Publicado: (2016)

Erratum: Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria
por: Gisslinger, H, et al.
Publicado: (2017)

Chordoma Characterization of Significant Changes of the DNA Methylation Pattern
por: Rinner, Beate, et al.
Publicado: (2013)

Prolonged follow‐up on lenalidomide‐based treatment for mucosa‐associated lymphoid tissue lymphoma (MALT lymphoma)—Real‐world data from the Medical University of Vienna
por: Kiesewetter, Barbara, et al.
Publicado: (2019)

First Line Systemic Treatment for MALT Lymphoma—Do We Still Need Chemotherapy? Real World Data from the Medical University Vienna
por: Kiesewetter, Barbara, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i9pn9313dv25vakjclqt4scbes