Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

BACKGROUND: The enzymes involved in de novo purine synthesis (DNPS), one of the basic processes in eukaryotic cells, transiently and reversibly form a dynamic multienzyme complex called the purinosome in the cytoplasm. The purinosome has been observed in a broad spectrum of cells, but some studies c...

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Detalles Bibliográficos
Autores principales: Baresova, Veronika, Skopova, Vaclava, Souckova, Olga, Krijt, Matyas, Kmoch, Stanislav, Zikanova, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066232/
https://www.ncbi.nlm.nih.gov/pubmed/30059557
http://dx.doi.org/10.1371/journal.pone.0201432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066232/
https://www.ncbi.nlm.nih.gov/pubmed/30059557
http://dx.doi.org/10.1371/journal.pone.0201432

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