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Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei

The sleeping sickness parasite Trypanosoma brucei has a complex life cycle, alternating between a mammalian host and the tsetse fly vector. A tightly controlled developmental programme ensures parasite transmission between hosts as well as survival within them and involves strict regulation of mitoc...

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Detalles Bibliográficos
Autores principales: Dewar, Caroline E., MacGregor, Paula, Cooper, Sinclair, Gould, Matthew K., Matthews, Keith R., Savill, Nicholas J., Schnaufer, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066258/
https://www.ncbi.nlm.nih.gov/pubmed/30020996
http://dx.doi.org/10.1371/journal.ppat.1007195